5050 bclc. Typically, diagnosis is late and median survival following diagnosis is approximately 6–20 months. 5050 bclc

 
 Typically, diagnosis is late and median survival following diagnosis is approximately 6–20 months5050 bclc  This means there is a single tumour of any size, or up to 3 tumours all less than 3 cm

The Barcelona Clinic Liver Cancer (BCLC) advanced stage (BCLC C) of hepatocellular carcinoma (HCC) includes a heterogeneous population, where sorafenib alone is the recommended treatment. This procedure is associated with objective tumor response rates of. Physical status. The existing 50/50 will continue to run. 1. bc. cat. Functional status of the liver. 36. The software delivers an easy to use gaming platform with eye-catching. Decide how many consecutive plays (up to 99) Set your wager - $1, $2, $5 or $10 per draw. Pacific Hold'Em Poker. Daily Grand & Extra. IBCC Credential Types BOARD OF CHRISTIAN PROFESSIONAL & PASTORAL COUNSELORS (BCPPC) Board Certified Biblical Counselor (BCBC) Basic Requirements: Identify and practice as a lay Christian counselor – small group facilitators, church-based lay counselors, hospice workers, registered nurses, bachelor level social workers, substance. Parent. If you have enrolled in BCLC's Voluntary Self-Exclusion/Game Break program please refrain from taking this survey. m. Edmonton Elks. . Claim a Prize. 2% of the patients (123 of 272) having an α-fetoprotein value below 400 ng/mL, compared with only 27. Results. The BCLC staging system is relatively unique given its incorporation of stage-based treatment recommendations . Components of this approach include: • Backbone Organization – The Center at Sierra HealthHypothesis: Using an algorithm for selection of patients with hepatocellular carcinoma (HCC) for surgery, Barcelona Clinic Liver Cancer (BCLC) classification stage B and stage C disease is not a contraindication. Close GameSense information panel What is GameSense? GameSense reinforces our focus on keeping it fun. BCLC staging and treatment strategy in 2022. 7M subscribers in the hockey community. INTRODUCTION. 2/4. These additional prizes are called MAXMILLIONS™. CD4+ T cells (CD4+) are the key to immunotherapy, but patients with HCC that have low CD4+ are rarely observed for clinical evidence. The expected outcome is expressed as median survival of each tumour stage according to the available scientific evidence. 1016/j. Performance status, AST, abdominal pain, and esophageal varices improved the discriminatory ability of CLIP. Play the lottery in BC and check winning numbers | BCLC Interestingly, patients with BCLC B n cancers also differed from patients with BCLC C n cancers in terms of α-fetoprotein values, with 45. 00. PDT. CFL Network. 2 BCLC Group, Liver Unit, ICMDM, IDIBAPS, Hospital Clinic of. Introduction Immunotherapy has become a new therapy for advanced hepatocellular carcinoma (HCC); however, its treatment results are considerably different. 3-8 In the last years, HCC management has profoundly changed because of improved diagnostic capacity, the refinement of prognosis assessment, and particularly. We would like to show you a description here but the site won’t allow us. was a $70. $2,500 CASH. The BCLC staging system is thought to be better than other staging systems for determining prognosis, given the inclusion of liver function and. You can play up to 15. BCLC stage A includes patients with just one nodule or 3 nodules under 3 cm. BC/49 & Extra. However, although this. Explore Hundreds Of Casinos Games, Check Lotto Numbers & Bet On Your Favourite Teams. Purolator courier bag: 2. Please complete and PRINT all requested information in a legible manner or mark N/A if not applicable. Geri Ann Frasch, of Sweden, has opened the Brockport/Clarkson Learning Center (BCLC) at 4099 Lake Road in Brockport. The BCLC staging system was developed based on a cohort consisting of mainly HCVinfected patients, and most patients had more advanced liver disease. BCLC staging system is based on four different variables with qualitative or quantitative assessment: child score (child A, child B, and child C); performance status (0–4); nodule size; and nodule. Conclusion: In our selected patient population, CLIP, CUPI, and GETCH were the most informative staging systems in predicting survival in. 8% vs 21. BCLC stage B (nodules out of Milan criteria without vascular invasion or extrahepatic metastasis, Child-Pugh class A or B, PS 0) is a candidate for TACE. m. Examining individual patient assessment for using TACE (transarterial. We sought to identify ideal candidates for Y90 by assessing survival and toxicities in this patient group. Lotto Max Numbers. 00. " The Hockey BC Team Canada 50/50 raffle is back for the World Juniors and monies raised will help support the growth of hockey in the Province of British Columbia. 2022 May;76(5):1237-1239. C. Published Sept. SCAN YOUR TICKETS FOR WINNERS. Wait for the draw to take place. Do you want to win big with better odds and bigger thrills? Check out the BC 50/50 Lotto winning numbers and see if you are one of the lucky winners. The front shaft is constructed to be slightly taller than the back shaft to offer a leg-lengthening effect as well as. Hepatocellular Carcinoma Primary liver cancer is the fourth most common tumor worldwide. Explore Hundreds Of Casinos Games, Check Lotto Numbers &. This Review discusses the current and emerging therapeutic landscape for treatment of advanced hepatocellular carcinoma, including molecular-targeted monotherapies, immuno-oncology monotherapies. 900. This treatment has also been performed as a second-line treatment in BCLC-C stage patients ineligible forthe anti-angiogenic drug Sorafenib, with similar results in terms of progression-free survival (6. Pacific Hold'Em Poker. 1 We provide insight into the updated BCLC 2022 guidelines and potential areas for improvement. BCLC Certificates for Bahamian ships must be obtained only from the. You can add Keno Bonus to your ticket and multiply your potential winnings by 1. 302 Found. The Toronto Blue Jays’ care organization Super September 50/50 grand prize is set to be the largest in major league baseball history and will turn the winner into an overnight multi-millionaire. See current and past Lotto 649 results on PlayNow, BCLC. 1/4. Workforce Skills. 0% (60 of 222) in patients with BCLC C n cancers (P < . Objective: This study reviewed the distribution of each tumor stage and each type of initial treatment modality among patients with primary hepatocellular carcinoma (HCC) treated at a tertiary tumor hospital between January 2003 and October 2013. Shop. Draw date: Friday May 13 at 12 p. Kristen Robinson tells us why it could have made that decision. 68437. Launching game - PlayNow Very few studies have compared BCLC and HKLC scores, and in European/North American populations the latter did not show a better prognostic performance than BCLC [23,30,31,32]. Poker Lotto. 579 and 0. As one of the most common and aggressive malignancies, hepatocellular carcinoma (HCC) ranks the second most fatal cancer globally []. 13, 2021, Lotto Max draw in Vancouver to check their tickets for the winning number: 1-14-17-20-28-32-38. Cadbury Schweppes plc v Halifax Share Dealing Ltd [2006] EWHC 1184 (Ch) 73. BCLC staging and treatment strategy in 2022. The BCLC staging system is a prognostic system and offers guidance for treatment decisions based on tumor burden, liver functional reserve, and performance status. Download a . Here's a breakdown of the prizes: Burnaby - $89k. " [In 2017], Burns Lake contributed to 4. The BCLC B sub-staging system could be an. MELDNa/MELD-Na Score for Liver Cirrhosis - MDCalc. Scratch & Win. Patients treated in accordance with the BCLC strategy received a higher proportion of curative treatments than those who did not (51. The classification takes the following variables into account 1,2: performance status (PS) Child-Pugh score. Keno & Keno Bonus. . BC Lions. You could be next!Columbia Lottery Corporation | BCLCPlay it smart by using our tools and playing within your limit. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for ~90% of. The innovative BCLC Colloquium Series offers a forum for promising junior and established senior scholars to present their work to some of America’s leading criminal law theorists. Tickets that win under $2000 do not require a mail declaration form to be completed. It is typically diagnosed late in the course of these diseases, and the median survival following diagnosis ranges from approximately 6 to 20. 10. GameSense involves learning how the games work and the odds of winning and losing. BCLC staging and treatment options according to level of evidence and approval status. Draws will occur at times as determined by BCLC, in its sole discretion, commencing on or after 4:06 a. There is a new draw every 3:30 minutes and each draw offers the chance to win $200,000. View All Events. The second novelty in this update is the recognition of liver transplantation (LT) as one of the main objectives. 00. Lightbody’s medical leave, to address the 'retail' typology of money laundering. BCLC will suspend or cancel a Program Member’s Points or other rewards if they have been barred, banned, or suspended. Many hepatologists in Asian countries have made efforts to adopt the principles of the BCLC staging system; in contrast, theyCanadians Announce 2021 Early Bird schedule. BCLC takes problem gambling seriously. The general consensus is that the BCLC system should be preferred for staging HCC as it is useful in predicting outcomes and planning treatment. $1. A retrospective, real-world study was conducted to. 22. • Most applicants will be able to complete their application in under 30 minutes if theyThe BCLC staging system has been validated by a surgically oriented European group 32. 8. $93,537. The expected outcome is expressed as median survival of each tumour stage according to the available scientific evidence. C. Winners. O. “When a winning ticket for a prize of $500,000 and above is set to expire, BCLC works to raise awareness through social media and media outreach to help remind players to check their tickets in the hopes of. More than 70% of patients with HCC are diagnosed at intermediate- or advanced-stage disease and are ineligible for curative treatment (1,2). Liver cancer classification. 01, likelihood χ 2 =57. Instantly find out if you’ve won with the simple ticket scanner. Keno is fast, fun and easy to play. The Court of Appeal confirmed that “a causal connection [must] exist between the personal actions of the shareholder or third party and some other act or omission constituting conduct of the company's affairs within Section 994”, applying Graham v Every [2015] 1 BCLC 41. Our staff is selected according to their personal qualities of warmth and empathy. Licensing@gov. Bucket List Adventures Await Kamloops Woman After $1-Million Lotto 6/49 Win. Licensing@gov. A winner from British Columbia is making sure she'll never forget the day she won a. C-index for training and validation cohorts (0. If you have enrolled in BCLC's Voluntary Self-Exclusion/Game Break program please refrain from taking this survey. 15-Nov. The offending allegations which failed to meet this test were struck. To be categorized as BCLC-B, patients should be asymptomatic and have no vascular invasion. 88 , 89 A subclassification consisting of 4 subgroups (B1-B4) has been proposed. The mortality due to rupture of HCC in. The School of Business is experiencing substantial and exciting growth. BC 50/50 tickets can be purchased in the following selection options: 1 selection for $1; 2 selections for $2; 3 selections for $3; 4 selections for $4; 6 selections for $5; or 15. Download Daily Grand Winning Numbers. Kelsey Hunden. C Lyle Lin elected free agency. C. BCLC stage B (nodules out of Milan criteria without vascular invasion or extrahepatic metastasis, Child-Pugh class A or B, PS 0) is a candidate for TACE. BCLC has an overall rating of 4. Check the latest Keno winning numbers here on PlayNow. Before applying for a gaming event licence, an applicant must review the event procedures within the Licensed Charitable Gaming Rules (PDF) to become familiar with the rules that must be followed. 5 of the Licensed Charitable Gaming Rules. Download a . This topic. 99. Don't miss your chance to win half of the jackpot. Contests & Promotions. To find out more about BCLC, come to a meeting or ride with us. We would like to show you a description here but the site won’t allow [email protected] x MELD x (140-Na) + 140. BC and Manitoba's Online Casino - Safe, secure and guaranteed. In the event of a tied frequency, the most recently draw numbers are shown first. At every Canucks home game, there is a 50/50 draw, where 50% of the money goes to the lucky winner, and 50% to the Canucks for Kids Fund. WINNERS: BC Lions 50/50 rules and information for all Lions regular season and playoff games: Tickets for the 50/50 Draw presented by belairdirect. BCLC takes problem gambling seriously. Key messages: Subclassifications of BCLC B and C stages are urgently needed and require validation in order to guide clinicians towards the most effective treatment. BC 50/50 Lotto is a fun and easy way to support your community and win big. Objective: To evaluate the survival outcomes of combined liver resection (LR) and radiofrequency ablation (RFA) on multi-focal hepatocellular carcinoma (HCC) in patients with Barcelona clinic liver cancer (BCLC) stage B. There is a new draw every 3:30 minutes and each draw offers the chance to win $200,000. Team Roster. OS worsened incrementally with higher TBS (5-year OS 77·9, 61 and 39 per cent for low,. Please sign your ticket with your full legal name in the front of the ticket and. edu. Must be 19 years or older to purchase a 50/50 ticket. 19 + to Play! "Actual odds of winning depend on # of tickets sold. We aimed to investigate the prognostic value of BDI and the stage of BDI in different staging systems. Effective Oct 02, 2023 to Jan 01, 2024. "Tickets. Minor League Baseball trademarks and copyrights are the property of Minor League Baseball. Management Challenges of Advanced HCC. 50/50 does not suggest that you have a 50% chance of winning — it just means half of the prize money is given to the province of British Columbia. C. See the latest winning numbers for Lotto Max right here to find out if you are due a payout. British Columbia Lottery Corporation | BCLCINTRODUCTION — Hepatocellular carcinoma (HCC) is an aggressive tumor that usually occurs in the setting of chronic liver disease and cirrhosis. Pacific Time on the following calendar date (the “Draw Day”). Download Daily Grand Download Extra. 66496730-01. The BCLC system classifies patients. Follow us on. Gambling events include raffles, bingos, poker, social occasion casinos, and wheels of fortune. BC 50/50 Lotto is a fun and easy way to support your community and win big. Poker Lotto. Buy Ticket Lotto 6/49 & Extra Nov 18, 2023 06 22 26 30 35 36 Bonus 25 06 12 72 89 $1 MILLION. March 3, 2021. Kelsey Hunden. In 42 cases, patients were treated with combination therapy. 48. Saskatchewan Roughriders. Download BCLC Lotto! and enjoy it on your iPhone, iPad and iPod touch. Lottery Corporation has finally given up a decade-long fight to keep a secret. Actually, BCLC stage-B, which is defined as intermediate stage, includes diverse patients having Child-Pugh grade-A and grade-B liver function with four or more tumors irrespective of size, or 2-3 tumors larger than 3 cm in maximal diameter, in the absence of cancer-related symptoms, macrovascular invasion, or extrahepatic spread. LI. The Vancouver Canadians have released the preliminary 2022 schedule. See current and past Lotto Max results on PlayNow, BCLC. Launching game - PlayNowVery few studies have compared BCLC and HKLC scores, and in European/North American populations the latter did not show a better prognostic performance than BCLC [23,30,31,32]. It determines cancer stage and patient prognosis based on tumour burden, severity of liver disease, and performance status . The aim of this study was to evaluate the BCLC system prospectively in a subsequent separate group of HCC. Draws every Wednesday and Saturday!Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. C. In 2010, The Disappearance of Haruhi Suzumiya was released and then now in 2022 the The Quintessential Quintuplets' movie will be released. Pacific Hold'Em Poker. are sold during each Lions home game at BC Place to benefit amateur football in British Columbia. 50/50, Regular Raffle, Bingo, etc. 5,21,22 Since the original publication of the BCLC algorithm in 1999, 23 its parameters have been used in most. Tools and resources to help you if gambling no longer feels like a game. Despite intensive surveillance programs, considerable recent therapeutic. Vancouver, B. There will be no big. This study sought to provide a. bc. Someone out there is. The Toronto Blue Jays’ Care Foundation's Super September 50/50 grand prize is set to be the largest in major league baseball history and will turn. 1/4. 1. BC: poker, blackjack, slots, lottery, sports, and bingo MB: poker, blackjack, slots, lottery and sports. Secondary efficacy endpoints included the objective response rate (ORR) and change in the sum of longest diameters (SLD) of target lesions from baseline per IRF RECIST 1. Experts discuss recent data surrounding emerging combinations of TACE plus systemic therapies for patients with BCLC stage B or C HCC. The largest lottery prize ever won in B. Design: Prospective cohort study. The Barcelona Clinic Liver Cancer (BCLC) staging system, which was first introduced in 1999, is the most commonly used worldwide. A BCLC stage of B (defined as intermediate-stage disease) corresponds to patients with a Child- Pugh grade A or B status diagnosed with multiple nodules without vascular invasion or extrahepatic metastasis. Instantly find out if you’ve won with the simple ticket scanner. The online 50/50 gives fans located in British Columbia along with fans attending games the chance to win during every Rockets home. With the live draws happening every 3:30 minutes you could win up to $200,000. This study compared the prognostic significance of staging between the American Joint Committee on Cancer 8th edition Tumor, Node, Metastasis (TNM) staging system and the Barcelona Clinic Liver Cancer (BCLC) classification in patients with hepatocellular carcinoma (HCC). bc. Effective August 25, 2022, licensees will no longer be permitted to scan and email bingo cards as per Section 10. 00. 🎙️ BC Lions On Tap. Schedule + Team. Contests & Promotions. Prince George - $73k. Don't miss your chance to win half of the jackpot. The Lotto! Certification Program is part of BCLC's commitment to provide you with the information and tools you will need to sell and validate lottery games with integrity. The Barcelona Clinic Liver Cancer (BCLC) classification offers a prognostic stratification of patients with hepatocellular carcinoma (HCC). Online. Saskatchewan Roughriders. 029. You'll cheer harder. This means the tumour is less than 2cm, you feel well (PS 0) and your liver is working normally (Child-Pugh A). One of these validated systems is the Barcelona-Clinic Liver Cancer staging system (BCLC). C, in conjunction with the Vancouver Canadians, bring you the 2023 50/50 raffle. We investigated preoperative drug-eluting bead transarterial. You can play up to 15 picks and 10 consecutive draws per ticket. Contests & Promotions. You will be asked to review and sign a new Game Break Enrolment Form, again specifying the new Game Break period you would like. 4. Hamilton Tiger-Cats. The Barcelona Clinic Liver Cancer (BCLC) classification offers a prognostic stratification of patients with hepatocellular carcinoma (HCC). Choose from the Biggest Selection of Wine, Beer & Spirits at a BCLIQUOR location near you. BC: poker, blackjack, slots, lottery, sports, and bingo MB: poker, blackjack, slots, lottery and sports. 22. BCLC will close the Encore Rewards Account and pay out the Points balance of a Program Members who has self-excluded. Shirley Suecroft. Click here to view the Half Season Ticket Plans. Of 10 patients with 0 stage HCC, 80% were treated according to the. 0. Tickets are 3 for $5 or 10 for $10 or 25 for $20. 27, 2023 8:00 a. BCLC takes problem gambling seriously. Each $1 play gives you 1 set of 6 numbers from 1 - 49. C. For liver cancer in adults, stages are also grouped according to how the cancer may be treated: Localized liver cancer has not spread outside the liver and can be removed by surgery. Make an appointment. The prognostic implication of Barcelona Clinic Liver Cancer (BCLC) substages in Asian patients with hepatocellular carcinoma (HCC) is still obscure. Each draw is complete after 20 numbers are. Re Cabot Global Ltd [2016] EWHC 2287 (Ch) 126. Congratulations to the Barcelona Clinic Liver Cancer (BCLC) group on the 2022 update of the staging, prognosis and treatment guidelines for hepatocellular carcinoma (HCC), which are commonly cited to guide clinical decision-making for HCC worldwide. $1,000 a DAY for LIFE. On the basis of the original BCLC stages, the overall. "While BCLC has addressed some of Dr. Materials and methods: A retrospective review. 99. Available from Monday to Friday from 8:00h to 18:30h. Background: For patients with complete response (CR) of Barcelona Clinical Liver Cancer (BCLC) stage B hepatocellular carcinoma (HCC), there is no consensus regarding the monitoring strategy. For more information, please contact Gaming. A licensee must have a separate licence for each type of gambling event it conducts (i. Winners. According to the BC Lottery Corporation (BCLC), a BC 50/50 ticket purchased in Prince George was drawn with the winning numbers to a total of $73,076. LABATT 50 ALE. 503 Background: Intermediate hepatocellular carcinoma is a heterogenous group of disease. Background/aims: The Barcelona Clinic Liver Cancer (BCLC) classification offers a prognostic stratification of patients with hepatocellular carcinoma (HCC). Overall. e. BCLC stage. C. Province of British Columbia. Congratulations Angie!60 votes, 17 comments. C. Draws every Wednesday and Saturday! Play the lottery in BC and check winning numbers | BCLC BC and Manitoba's Online Casino - Safe, secure and guaranteed. BC/49 & Extra. JURA 14-YEAR-OLD AMERICAN RYE CASK - $89. Subsequently, a BCLC very early stage (0) was added to the classification which included patients with well-preserved liver functional reserve and asymptomatic with a single tumor of size less than 2 cm . Bclc holds a $1,000,000 insurance policy with Atlantic Casualty Insurance Company. Shirley Suecroft. On Sale (until Nov 25) More Info. ) The only potentially curative treatment options are resection and liver transplantation. 1. Abby B. 3311. C. We would like to show you a description here but the site won’t allow us. The AASLD modifies the BCLC staging systems to better support clinical practices: the performance status (PS) scoring for BCLC stages 0, A, and B has been changed from 0 to 0–1; and the PS for BCLC stage C has been expanded to 0–2. Play the lottery in BC and check winning numbers | BCLCThe official lottery app for the British Columbia Lottery Corporation (BCLC). Step 3: Choose your betting option (e. The British Columbia Lottery Corporation is a Canadian Crown corporation offering a range of gambling (AKA gaming) products including lottery tickets, casinos and legal online gambling. If you have any questions, please contact BCLC Customer Support at 74 West Seymour Street Kamloops, BC V2C 1E2 or telephone 1-877-706-6789. doi: 10. The BCLC staging system. $1. There have been major advances in the armamentarium for hepatocellular carcinoma (HCC) since the last official update of the Barcelona Clinic Liver Cancer (BCLC) prognosis and treatment strategy published in 2018 [1–7]. 3. ”. These are the products poured at the event: CANADIAN CLUB 15-YEAR-OLD CC CLASSIC SHERRY CASK - $75. British College La Cañada. Introduction: Stereotactic Body Radiotherapy (SBRT) emerged as a valuable option in early to advanced-stage Hepatocellular Carcinoma (HCC) as defined by Barcelona Clinic Liver Cancer (BCLC) system. $ 65. The treatment options for the. But the agony of anticipation will make your victory taste that much sweeter. Join for free and choose your welcome bonus. It is estimated that, by 2025, >1 million individuals will be affected by liver cancer annually 3. 5, 34 EASL guidelines classify large solitary HCC lesions as BCLC Stage A and recommend. Download Keno Winning Numbers. At the stadium, tickets are sold in-game from the time doors open at BC Place until the end. 1. BCLC Staging System BCLC StagingSystem The Barcelona Clinic Liver Cancer (BCLC) staging system used by AASLD identifies 4 stages, which include imaging-based tumorsize, number, macro-vascular invasion, and nodal and extra-hepatic metastases, as well as clinical criteria (according to Child-Pugh score and performance status). The BCLC staging system. The proportion of patients in each BCLC stage receiving a treatment that was or was not recommended for that particular stage is shown in figure 2. The Barcelona Clinic Liver Cancer (BCLC) Staging System is widely. %PDF-1. Intermediate stage HCC, as defined by the Barcelona Clinic Liver Cancer (BCLC) system stage B, represents up to 30% of patients at diagnosis and encompasses a broad spectrum of tumor burden. See current and past Lotto Max results on PlayNow, BCLC. Powered by Tengine. $1. New section: Technology Facilitated Gaming Events (Non -ERS)The BCLC proposal constitutes an evolving approach and it has been regularly updated and refined, incorporating all advancements that emerged since its original publication. stage C: advanced. Millions of dollars in prizes have been won and thousands of British Columbians are better off because nearly 6,000 charitable and community organizations can continue to do. Read Story $ 250,000. The study population compris. 1. We recently demonstrated the BCLC's peculiar prognostic ability in a retrospective cohort of HCC patients. All Bahamian ships of more than 1,000 gross tonnage require a valid BCLC Certificate attesting that insurance or other financial security is in place to cover the registered owner’s liabilities under the Bunker Convention. There are four chances to win every day 1:00 pm, 3:00 pm, 6:00 pm, and 9:00 pm. Citation, DOI, disclosures and article data. However, the classifications of early (BCLC-A) and intermediate (BCLC-B) stage HCC remain controversial. You will find below a list of unclaimed prizes for Scratch & Win tickets (B. bclc . Each draw is complete after 20 numbers are. Hepatocellular carcinoma (HCC) is a major public health problem worldwide for which the incidence and mortality are similar, pointing to the lack of effective treatment options. radiologic tumor extent. Hepatocellular carcinoma occurs mainly in the context of cirrhosis, hepatitis B or C virus infection, or non. BC 50/50. Methods: This single-institutional retrospective. Tuesday, December 7, 2021, 12:45 pm. e. 1, 2 Major leading international liver study groups such as the American Association for the Study of Liver Diseases, the American Gastroenterological. 668), improving prognosis prediction. The B. BCLC intermediate stage includes a heterogeneous patient population with varying tumor characteristics and liver function, which poses serious challenges for therapeutic management .